Measuring prothrombin time: Too long may be too short!

The QT interval: too long, too short or just right.

Is the travel time of private roads too short , too long , or just right ? †

We consider price and service-quality setting in oligopolistic markets for congestible services, applied to the case of private roads. Previous studies show that parallel competitors set a volume/capacity ratio (and thereby a travel time or service quality) that is socially optimal if they take the actions of the others as given. We find that this result does not hold when capacity and toll set...

Reducing Cardiovascular Risk: Too Little, Too Late, Too Short-Term

Vascular diseases in general, and cardiovascular disease in particular, are diseases of mass destruction, killing more people in the Western world (and increasingly in the developing world) than world wars. Each year, coronary heart disease kills over half a million Americans and over 100 000 British citizens each year, often prematurely (WHO online). A combination of migration, epidemiological...

Listen Too Closely and You May Be Confused

Among the most basic simplifying assumptions of modern communications security is the notion that most communication channels should, by their very nature, be considered vulnerable to interception. It has long been considered almost reckless to suggest depending on any supposed intrinsic security properties of the network itself1, and especially foolish in complex, decentralized, heterogeneousl...

Current treatment of renal artery aneurysms may be too aggressive.

OBJECTIVE Most studies recommend repair of renal artery aneurysms (RAAs) >2 cm in diameter in asymptomatic patients, but other studies have suggested that their natural history may be more benign. We hypothesized that rupture and death in patients with asymptomatic RAAs is low and that current recommendations for RAA treatment at 2 cm may be too aggressive. METHODS Retrospective review of all...